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Project Title: Longitudinal Assessment of chronic kidney disease (CKD) prevalence rates and major risk factors in Semirural sub-Saharan Africa

Project Description: RenalTWO is a prospective, non-interventional observational study open to patients seeking primary care in the Bagamoyo district hospital (BDH) and two associated dispensaries (Fukayosi and Yombo) in the catchment area. The aim of RenalTWO is to assess the prevalence of chronic kidney disease (CKD) and associated risk factors using state-of-the-art assessment and classification methods. Despite multiple repeated requests by the scientific community and global public health authorities over the past decade, this important knowledge gap... RenalTWO is a prospective, non-interventional observational study open to patients seeking primary care in the Bagamoyo district hospital (BDH) and two associated dispensaries (Fukayosi and Yombo) in the catchment area. The aim of RenalTWO is to assess the prevalence of chronic kidney disease (CKD) and associated risk factors using state-of-the-art assessment and classification methods. Despite multiple repeated requests by the scientific community and global public health authorities over the past decade, this important knowledge gap has not been addressed in the sub-Saharan Africa (SSA) region to date. Understanding the prevalence and the risk factors for CKD in the setting of semi-rural Tanzania js important for regional and national health care planning. RenalTWO is expecting to enrol 1200 patients over the duration of 6 months with multiple follow-up visits over a full calendar year. Further, we aim to support capacity building in the BDH and Fukayosi, and Yombo dispensaries necessary for detectin defined risk si natures for the develo ment of CKD. The project is a continuation of the research group's cross-sectional approach to the CKD prevalence and risk factor study (RenalOne), which was successfully conducted in 2011 in the BDH — together with the same partner organizations from Switzerland. The Swiss Tropical and Public Health Institute is a long-time collaborator and is in a close relationship with the University Hospital Basel and the Ifakara Health Institute. The knowledge gained and the collated epidemiological evidence will support future upscaljng and sustainable capacity building, as well as the implementation of critically needed screening, diagnostic, prevention, and management strategies — tailored to the settinas of semirural in Tanzania and other SSA countries.


Principal Investigator : Ally Olotu

Department Name :

Time frame: (2023-04-01) - (2025-03-31)

Funding Partners
Swiss Tropical and Public Health Institute (Normal)
External Collaborating Partners
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